Bioenhancers from mother nature: an overview

Neoatherosclerosis: fooling mother nature.

Transplantation tolerance: fooling mother nature.

Foreignness is threatening. The immune system, the primary arbiter of self and nonself, will reject an organ transplant unless constrained by life-long administration of multiple immune suppressive drugs. Immunosuppressive therapy, while facilitating graft success, heightens susceptibility to infection and the development of malignancy. The challenge then is to educate the immune system to tole...

Natural Bioenhancers: Current Outlook

Pharmaceutical companies around the globe have always been in the urge of discovering innovative blockbuster drugs for various ailments by spending billions of dollars for the drug discovery programmes. Although identification of new chemical entities (NCEs) with alternate mode of actions for diseases is a primary concern for the pharmaceutical companies, application of innovative techniques an...

Prevention of mother-to-child transmission of HIV--an overview.

With the human immunodeficiency virus (HIV) epidemic showing a shift towards women and young people, the increasing seroprevalence among women will result in an increase in the mother-to-child transmission of HIV. The vast majority of HIV-positive children worldwide acquire the infection through vertical transmission. The discovery of successful interventions that interrupt this transmission ha...

Maternal immunisation: collaborating with mother nature.

Maternal immunisation has the potential to substantially reduce morbidity and mortality from infectious diseases after birth. The success of tetanus, influenza, and pertussis immunisation during pregnancy has led to consideration of additional maternal immunisation strategies to prevent group B streptococcus and respiratory syncytial virus infections, among others. However, many gaps in knowled...